Differing obstetric outcomes of rosacea fulminans in pregnancy: report of three cases with review of pathogenesis and management.

R Jarrett, R Gonsalves, A V Anstey

Journal: Clinical and experimental dermatology 2011;35(8):888-91

PMID: 20456381

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Abstract

Rosacea fulminans (RF) is a rare facial dermatosis characterized by the sudden onset of severe facial inflammation consisting of numerous pustules, cystic swellings and coalescing sinuses. The standard treatment is the retinoid drug isotretinoin in combination with systemic corticosteroids or with high-dose oral tetracycline antibiotics. We report three recent cases of RF in pregnancy with differing obstetric outcomes: an intrauterine death, a termination of pregnancy, and a normal vaginal delivery. The pathogenesis of RF is considered and therapeutic options in pregnancy are reviewed.

Address: Department of Core Medicine, Bristol Royal Infirmary, United Bristol Healthcare Trust, Bristol, UK. [email protected]

DOI: 10.1111/j.1365-2230.2010.03846.x

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MeSH Terms: Abortion, Induced, Acne Vulgaris, Adult, Anti-Bacterial Agents, Dermatologic Agents, Diabetes, Gestational, Drug Therapy, Combination, Erythromycin, Facial Dermatoses, Female, Fetal Death, Glucocorticoids, Humans, Isotretinoin, Oligohydramnios, Prednisolone, Pregnancy, Pregnancy Complications, Pregnancy Outcome, Rosacea, Treatment Outcome