Chemical constituents and biological applications of the genus Symplocos.

Ruchi Badoni, Deepak K Semwal, Sudhir K Kothiyal, Usha Rawat

Journal: Journal of Asian natural products research 2011;12(12):1069-80

PMID: 21128148

Abstract

The genus Symplocos has been reviewed for its chemical constituents and biological activities including traditional importance of some common species. The plants of this genus contain terpenoids, flavonoids, lignans, phenols, steroids, alkaloids, and iridoids. Terpenoids are the major constituents within the genus Symplocos and most of them exhibit antiproliferative effects. Some phenolic glycoside derivatives showed inhibitory activity against snake-venom phosphodiesterase I and human nucleotide pyrophosphatase phosphodiesterase I. The members of genus Symplocos are well known for their traditional uses in the treatment of various diseases like leprosy, gynecological disorders, ulcers, leucorrhea, menorrhagia, malaria, and tumefaction. The aim of the present paper is to review the comprehensive knowledge of the plants of this genus including the traditional uses, chemistry, and pharmacology.

Address: Department of Chemistry, HNB Garhwal University, Srinagar, Uttarakhand, India.

DOI: 10.1080/10286020.2010.532789

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MeSH Terms: Alkaloids, Anti-Bacterial Agents, Anti-HIV Agents, Anti-Inflammatory Agents, Antidiarrheals, Antineoplastic Agents, Phytogenic, Antioxidants, Central Nervous System Agents, Chymotrypsin, Female, Flavonoids, Glycosides, Hemolytic Agents, Humans, Iridoids, Lignans, Magnoliopsida, Molecular Structure, Parasympatholytics, Phosphodiesterase Inhibitors, Plants, Medicinal, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Snake Bites, Steroids, Terpenes