Disseminated superficial actinic porokeratosis: a treatment review.

Hadas Skupsky, Jonathan Skupsky, Gary Goldenberg

Journal: The Journal of dermatological treatment 2012;23(1):52-6

PMID: 20964569

Abstract

Disseminated superficial actinic porokeratosis (DSAP) is a chronic disorder of keratinization characterized by numerous papules and plaques distributed over sun-exposed sites. Treatments are poorly standardized and several investigational therapies have demonstrated limited success in treating DSAP. To our knowledge, there have been no systematic reviews of the literature regarding the treatment of this disease. Herein, we review recent studies pertaining to the treatment of DSAP and evaluate the level of evidence for each of these therapeutic modalities.

Address: University of Maryland School of Medicine, Baltimore, MD, USA.

DOI: 10.3109/09546634.2010.495381

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MeSH Terms: Aminolevulinic Acid, Aminoquinolines, Anti-Inflammatory Agents, Non-Steroidal, Cholecalciferol, Diclofenac, Fluorouracil, Humans, Imiquimod, Immunosuppressive Agents, Interferon Inducers, Laser Therapy, Photochemotherapy, Photosensitizing Agents, Porokeratosis, Retinoids, Vitamins