Recent advances in the treatment of eosinophilic esophagitis.

Glenn T Furuta, Dan Atkins, Shauna Schroeder

Journal: Expert review of clinical immunology 2011;6(6):929-37

PMID: 20979557

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Abstract

First described nearly 20 years ago, eosinophilic esophagitis (EoE) is an inflammatory disease of the esophagus characterized by eosinophilic infiltration of the esophageal epithelium. Over 50% of the current literature on EoE has been published in the last 3 years, signaling both a rising incidence and increased recognition of this disorder. Treatment options available for patients with EoE include dietary management and/or pharmacologic therapy. An individualized approach to treatment is preferred, with an emphasis on patient-parental preference. The objective of this article is to discuss the current and future treatment options for EoE.

Address: University of Colorado Denver School of Medicine, Denver, CO, USA; The Children's Hospital Denver, 13123 East 16th Avenue, B290, Aurora, CO 80016, USA.

DOI: 10.1586/eci.10.65

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MeSH Terms: Antibodies, Monoclonal, Diet Therapy, Eosinophilic Esophagitis, Humans, Immunotherapy, Interleukin-13, Interleukin-5, Mucous Membrane, Patient Preference, Precision Medicine, Proton Pump Inhibitors, Th1-Th2 Balance