Chemistry and pharmacological action of caffeoylquinic acid derivatives and pharmaceutical utilization of chwinamul (Korean Mountainous vegetable).

Hee-Juhn Park

Journal: Archives of pharmacal research 2011;33(11):1703-20

PMID: 21116772

Full Text on Ovid Technologies, Inc. View on PubMed

Abstract

Chwinamul is a mountainous vegetable that refers to several species belonging to the family Compositae. Chwinamul has been used as a side dish or a medicinal herb to treat hypercholesterolemia, diabetes, common cold, atherosclerosis, and cardiovascular disease. Caffeoylquinic acids (CQs) are present in high levels in chwinamul, though caffeoyltartaric acids (CTs) are often occurred in the vegetables of Compositae. Here I review the chemical and pharmaceutical aspects of CQs and CTs. In particular, ¹³C-NMR data and CQ stereochemistry are discussed. CQ derivatives have antioxidative, peroxynitrite-scavenging, hepatoprotective, antiviral, antiobese, and antidiabetic activities.

Address: Department of Pharmaceutical Engineering, Sangji University, Wonju, Korea. [email protected]

DOI: 10.1007/s12272-010-1101-9

Link outs

Free resources

Medical:

https://medlineplus.gov/herbalmedicine.html

Other Literature Sources:

https://www.lens.org/lens/search/patent/list?q=ref...

Research Materials:

https://antibodies.cancer.gov/detail/CPTC-TTR-1

Subscription / membership required

Full Text Sources:

MeSH Terms: Asteraceae, Caffeic Acids, Humans, Korea, Peroxynitrous Acid, Phytotherapy, Plant Preparations, Plants, Medicinal, Quinic Acid, Stereoisomerism, Tartrates, Vegetables