Allergy and its relation to Meniere's disease.

Karen I Berliner, M Jennifer Derebery

Journal: Otolaryngologic clinics of North America 2010;43(5):1047-58

PMID: 20713244

Full Text on Elsevier Science View on PubMed

Abstract

Ménière's disease (MD), which by definition is idiopathic, has been ascribed to various causes, including inhalant and food allergies. Patients with MD report higher rates of allergy history and positive skin or in vitro tests compared with a control group of patients with other otologic diseases and to the general public. Recent immunologic studies have shown higher rates of circulating immune complexes, CD4, and other immunologic components in patients with MD compared with normal controls. Published treatment results have shown benefit from immunotherapy and/or dietary restriction for symptoms of MD in patients who present with allergy and MD.

Address: Clinical Studies Department, House Ear Institute, 2100 West Third Street, 5th Floor, Los Angeles, CA 90057, USA. [email protected]

DOI: 10.1016/j.otc.2010.05.004

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MeSH Terms: Antigen-Antibody Complex, Antigens, CD, Betahistine, Desensitization, Immunologic, Diet, Ear, Inner, Histamine Agonists, Humans, Immunity, Innate, Immunoglobulin E, Immunotherapy, Meniere Disease, Migraine Disorders, Skin Tests, Virus Diseases