Catheter-related thrombosis in children with intestinal failure and long-term parenteral nutrition: how to treat and to prevent?

Merit M Tabbers, C Heleen van Ommen

Journal: Thrombosis research 2011;126(6):465-70

PMID: 20870276

Full Text on Elsevier Science View on PubMed

Abstract

Survival of children with chronic intestinal failure has increased as result of administration of home parenteral nutrition. Crucial for the successful management of home parenteral nutrition is the availability of an adequate central venous access. Venous access can be fraught by episodes of catheter-infection, recurrent replacements of catheters and finally catheter-related thrombosis. Management and prevention of catheter-related thrombosis are of vital importance. For patients with compromised venous access, alternative measures are reported, most of them used as a bridge to bowel transplantation.

Address: Department of Pediatrics (Pediatric Hematology), Emma Children's Hospital/Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands. [email protected]

DOI: 10.1016/j.thromres.2010.08.027

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MeSH Terms: Catheterization, Central Venous, Child, Humans, Intestinal Diseases, Parenteral Nutrition, Home, Thrombosis