Medical treatment of pediatric status epilepticus.

Nicholas S Abend, Ana M Gutierrez-Colina, Dennis J Dlugos

Journal: Seminars in pediatric neurology 2011;17(3):169-75

PMID: 20727486

Full Text on Elsevier Science View on PubMed

Abstract

Status epilepticus (SE) is a common pediatric neurologic emergency that refers to a prolonged seizure or recurrent seizures without a return to baseline mental status between seizures. Appropriate treatment strategies are necessary to prevent prolonged SE and its associated morbidity and mortality. This review discusses the importance of a rapid and organized management approach, reviews data related to commonly utilized medications including benzodiazepines, phenytoin, phenobarbital, valproate sodium, and levetiracetam, and then provides a sample SE management algorithm.

Address: Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA. [email protected]

DOI: 10.1016/j.spen.2010.06.005

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MeSH Terms: Anticonvulsants, Child, Clinical Protocols, Humans, Status Epilepticus