Medical treatment of uncomplicated diverticular disease of the colon: any progress?

Clinical evidence supports a therapeutic approach to uncomplicated, symptomatic diverticular disease of the colon by means of increased fiber intake and cyclic administration of the non absorbable antibiotic agent rifaximin polymorph-alpha. Alternate treatments such as mesalazine and probiotics have been recently proposed but no definitive conclusions on their efficacy can be drawn until larger, randomized placebo-controlled studies will be available.