Radical trachelectomy for clear cell carcinoma of the cervix in a 6-year old: a case report, review, and description of the surgical technique.

Felicia C Lester, Diana L Farmer, Joseph T Rabban, Lee-May Chen

Journal: Journal of pediatric surgery 2010;45(8):E1-5

PMID: 20713196

Full Text on Elsevier Science View on PubMed

Abstract

Clear cell carcinoma is a rare pediatric cervical cancer, seen primarily in the setting of in utero diethylstilbesterol exposure. Historically, this type of cancer has been treated with radical hysterectomy and lymph-node dissection, rendering patients incapable of carrying a pregnancy in the future. We describe a young patient with clear cell carcinoma of the cervix who, through a multidisciplinary collaboration, was managed by a fertility-sparing alternative surgical approach--a radical trachelectomy. We present the surgical technique and review the current evidence regarding the use of radical trachelectomy as a fertility-sparing procedure in young patients with cervical cancer.

Address: Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, MA 02120, USA. [email protected]

DOI: 10.1016/j.jpedsurg.2010.05.032

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MeSH Terms: Adenocarcinoma, Clear Cell, Adult, Cervix Uteri, Child, Female, Fertility, Gynecologic Surgical Procedures, Humans, Lymph Node Excision, Pregnancy, Treatment Outcome, Uterine Cervical Neoplasms