Insights into developmental muscle metabolism through the use of 31P-magnetic resonance spectroscopy: a review.

Alan R Barker, Neil Armstrong

Journal: Pediatric exercise science 2010;22(3):350-68

PMID: 20814032

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Abstract

(31)phosphorous-magnetic resonance spectroscopy ((31)P-MRS) has become an extremely valuable technique to investigate changes in muscle metabolism noninvasively and in vivo. The purpose of this article is to critically review how (31)P-MRS has contributed to current understanding of muscle metabolic function in healthy children and adolescents. In addition, an overview of the basic principles of (31)P-MRS and its application to the study of muscle metabolism is provided and discussed in relation to child-specific methodological concerns when using this technique.

Address: Children's Health and Exercise Research Centre, School of Sport and Health Sciences, University of Exeter, UK.

DOI: 10.1123/pes.22.3.350

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MeSH Terms: Adenosine Triphosphate, Adolescent, Child, Energy Metabolism, Exercise, Humans, Hydrogen-Ion Concentration, Magnetic Resonance Spectroscopy, Muscle Development, Muscle, Skeletal, Phosphorus