Hyperzincemia from ingestion of denture adhesives.

David H Pashley, Ricardo M Carvalho, Arzu Tezvergil-Mutluay

Journal: The Journal of prosthetic dentistry 2010;103(6):380-3

PMID: 20493327

Full Text on Elsevier Science View on PubMed

Abstract

The purpose of this article is to review the recent literature that documents the serious adverse systemic effects of prolonged, excessive zinc ingestion from the overuse of denture adhesives. This condition causes elevation of serum zinc levels that result in depression of serum copper. The low serum copper levels cause bone marrow depression and widespread sensory and motor neuropathies. Epidemiologic studies revealed the source of excessive zinc intake to be from overuse of denture adhesives. Denture patients must be advised of the risks of prolonged overuse of denture adhesives.

Address: Department of Prosthetic Dentistry, Institute of Dentistry, University of Turku, Turku, Finland.

DOI: 10.1016/S0022-3913(10)60081-9

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MeSH Terms: Adhesives, Copper, Denture Retention, Humans, Metallothionein, Polyneuropathies, Zinc