Secondary metabolites from Inula britannica L. and their biological activities.

Abdul Latif Khan, Javid Hussain, Muhammad Hamayun, Syed Abdullah Gilani, Shabir Ahmad, Gauhar Rehman, Yoon-Ha Kim, Sang-Mo Kang, In-Jung Lee

Journal: Molecules (Basel, Switzerland) 2010;15(3):1562-77

PMID: 20336001

Abstract

Inula britannica L., family Asteraceae, is used in traditional Chinese and Kampo Medicines for various diseases. Flowers or the aerial parts are a rich source of secondary metabolites. These consist mainly of terpenoids (sesquiterpene lactones and dimmers, diterpenes and triterpenoids) and flavonoids. The isolated compounds have shown diverse biological activities: anticancer, antioxidant, anti-inflammatory, neuroprotective and hepatoprotective activities. This review provides information on isolated bioactive phytochemicals and pharmacological potentials of I. britannica.

Address: School of Applied Biosciences, Kyungpook National University, Korea.
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