Egg white protein-bonded columns and their applications.

Y Oda

Journal: Se pu = Chinese journal of chromatography 2003;18(6):508-17

PMID: 12541737

Abstract

Egg white protein-bonded columns were developed for HPLC. These columns can be used under aqueous mobile phase and separate various kinds of drug enantiomers. Hyphenated techniques using protein-bonded columns with LC/MS and/or column switching have been recognized as integral methods in pharmaceutical research to analyze drug enantiomers. Therefore, these methods are very useful for research fields of pharmacokinetics and pharmacology.

Address: Laboratory of Seeds Finding Technology, Eisai Co. Ltd, Tsukuba Ibaraki 300-2635, Japan. [email protected]

MeSH Terms: Anti-Inflammatory Agents, Non-Steroidal, Avidin, Chromatography, High Pressure Liquid, Conalbumin, Donepezil, Egg White, Flavoproteins, Indans, Ketoprofen, Piperidines, Stereoisomerism