New platinum and ruthenium complexes--the latest class of potential chemotherapeutic drugs--a review of recent developments in the field.

Amr Amin, Michael A Buratovich

Journal: Mini reviews in medicinal chemistry 2010;9(13):1489-503

PMID: 20205631

Abstract

New Platinum and Ruthenium complexes display antitumour and antimetastatic potentials and lower host toxicities. This mini-review examines some the more recent developments in this field, and explores their interactions with biologically-relevant species. The article also refers to more recent work in the area of molybdenum and copper(II) chemistry.

Address: Department of Biology, UAE University, P.O. Box 17551, UAE. [email protected]

DOI: 10.2174/138955709790361566

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MeSH Terms: Antineoplastic Agents, Drug Screening Assays, Antitumor, Humans, Neoplasms, Platinum Compounds, Ruthenium Compounds