Cardiac Purkinje cells.

Penelope A Boyden, Masanori Hirose, Wen Dun

Journal: Heart rhythm 2011;7(1):127-35

PMID: 19939742

Full Text on Elsevier Science View on PubMed

Abstract

Purkinje cells are specialized for rapid propagation in the heart. Furthermore, Purkinje fibers as the source as well as the perpetuator of arrhythmias is a familiar finding. This is not surprising considering their location in the heart and their unique cell ultrastructure, cell electrophysiology, and mode of excitation-contraction coupling. This review touches on each of these points as we outline what is known today about Purkinje fibers/cells.

Address: Department of Pharmacology, Columbia University, New York, NY, USA. [email protected]

DOI: 10.1016/j.hrthm.2009.09.017

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MeSH Terms: Action Potentials, Arrhythmias, Cardiac, Atrioventricular Node, Bundle of His, Calcium, Calcium Channels, Humans, Myocardium, Purkinje Fibers, Sarcoplasmic Reticulum