Apiaceae Family an Important Source of Petroselinic Fatty Acid: Abundance, Biosynthesis, Chemistry, and Biological Proprieties.

Ahmed Hajib, Said El Harkaoui, Hasnae Choukri, Aya Khouchlaa, Sarra Aourabi, Naoual El Menyiy, Abdelhakim Bouyahya, Bertrand Matthaeus

Journal: Biomolecules 2023;13(11):1675

PMID: 38002357

Abstract

Petroselinic fatty acid (PeFA) is considered a rare fatty acid and one of the most important fatty acids in the Apiaceae family. Its content varies depending on plant species, geographical origin, extraction method, ripeness, etc. Indeed, reported levels of petroselinic fatty acid range from 10.4 to 75.6% (in anise seed oil), 1 to 81.9% (in coriander seed oil), 28.5 to 57.6% (in caraway seed oil), 49.4 to 75.6% (in celery seed oil), 41.3 to 61.8% (in caraway seed oil), 79.9 to 87.2% (in dill seed oil), 43.1 to 81.9% (in fennel seed oil), and 35 to 75.1% (parsley seed oil). In this review, we also show current knowledge about genes encoding biosynthesis, from the desaturation of 16:0-ACP to petroselinic acid stored in triacylglycerol in the seeds. Furthermore, petroselinic acid is not related to the synthesis of ABA. PeFA was successfully isolated from Apiaceae family plant seeds in order to study their reactivity and biological activities. Several investigations showed that this fatty acid has a wide range of biological potentials, including antidiabetic, antibacterial, and antifungal activities. In cosmetics, PeFA alone or in association with other active compounds has interesting applications as an anti-inflammatory agent for the treatment of skin, hair, and nail disorders.

Address: Laboratory of Bioactive and Molecules of Interest, National Agency of Medicinal and Aromatic Plants (NAMAP), Taounate 34000, Morocco.; Department of Safety and Quality of Cereals, Max Rubner-Institut, Federal Research Insitute for Nutrition and Food, Schützenberg 12, D-32756 Detmold, Germany.; International Center for Agricultural Research in the Dry Areas, Rabat 10000, Morocco.; Laboratory of Biochemistry, National Agency of Medicinal and Aromatic Plants (NAMAP), Taounate 34000, Morocco.; Laboratory of Pharmacology, National Agency of Medicinal and Aromatic Plants (NAMAP), Taounate 34000, Morocco.; Laboratory of Human Pathologies Biology, Faculty of Sciences, Mohammed V University in Rabat, Rabat 10106, Morocco.
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