Malacoplakia presenting with obstructive nephropathy with bilateral ureter involvement.

Lorin M Sanchez, Sean I Sanchez, James L Bailey

Journal: Nature reviews. Nephrology 2009;5(7):418-22

PMID: 19556995

Full Text on Nature Publishing Group View on PubMed

Abstract

BACKGROUND

A 48-year-old woman with chronic urinary tract infections presented with uremia. Imaging studies revealed bilateral hydronephrosis and segmental ureteral thickening.

INVESTIGATIONS

Physical examination, urine and blood analysis, radiography of the chest, chest CT, abdominal and pelvis CT, renal ultrasonography, cystoscopy, anterograde pyelogram, bladder biopsy.

DIAGNOSIS

Malacoplakia involving bilatateral ureters and bladder; cavitary pneumonia.

MANAGEMENT

Hemodialysis, placement of bilateral percutaneous nephrostomy tubes, administration of ciprofloxacin, ascorbic acid and bethanechol.

Address: Emory University School of Medicine, Renal Division, Atlanta, GA 30322-2525, USA. [email protected]

DOI: 10.1038/nrneph.2009.86

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MeSH Terms: Adult, Chronic Disease, Female, Humans, Hydronephrosis, Malacoplakia, Ureteral Obstruction