Possible therapy for ALS based on the cyanobacteria/BMAA hypothesis.

Walter G Bradley

Journal: Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 2010;10 Suppl 2():118-23

PMID: 19929743

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Abstract

Although the cyanobacteria/BMAA hypothesis of the cause of ALS and other age-related neurodegenerative diseases remains to be proven, it is not too early to ask whether treatment would be possible if the hypothesis were correct. This paper reviews the possible ways that chronic BMAA neurotoxicity could be prevented or treated.

Address: Department of Neurology, Miller School of Medicine, University of Miami, 1120 NW 14 Street, Miami, Florida 33136, USA. [email protected]

DOI: 10.3109/17482960903285951

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MeSH Terms: Amino Acids, Amino Acids, Diamino, Amino Acids, Dicarboxylic, Amino Acyl-tRNA Synthetases, Amyotrophic Lateral Sclerosis, Cyanobacteria, Enzyme Inhibitors, Hair, Humans, Neurotoxins, Protein Transport