Pituitary Apoplexy-associated Cerebral Salt Wasting Syndrome: A Case Report and Literature Review.

Jialu Wu, Zhe Yan, Bo Li, Xijie Yu, Hui Huang

Journal: Clinical therapeutics 2023;45(12):1293-1296

PMID: 37778916

Full Text on Elsevier Science View on PubMed

Abstract

PURPOSE

This is a case report of a patient experiencing hyponatremia who was ultimately diagnosed with pituitary apoplexy-associated cerebral salt wasting syndrome (CSWS).

METHODS

Laboratory tests, clinical evaluations, and magnetic resonance imaging were performed by specialists.

FINDINGS

The patient presented with severe headache, thirst, and polyuria. Results of laboratory tests indicated hyponatremia, decreased plasma osmolality, and elevated urine osmolality. Fluid restriction worsened the situation, and normal saline treatment helped return serum sodium and chloride levels to normal. Pituitary apoplexy-associated CSWS was finally considered.

IMPLICATIONS

Pituitary apoplexy is a rare but reasonable etiology for CSWS with hyponatremia. Saline therapy is usually effective.

Address: Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, PR China.; Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, PR China. Electronic address: [email protected].

DOI: 10.1016/j.clinthera.2023.09.012

Link outs

Subscription / membership required

Full Text Sources:

MeSH Terms: Humans, Hyponatremia, Pituitary Apoplexy, Inappropriate ADH Syndrome