Small molecule mimics of hydrogenases: hydrides and redox.

Frédéric Gloaguen, Thomas B Rauchfuss

Journal: Chemical Society reviews 2009;38(1):100-8

PMID: 19088969

Free Full Text on PubMed Central View on PubMed

Abstract

This tutorial review is aimed at chemical scientists interested in understanding and exploiting the remarkable catalytic behavior of the hydrogenases. The key structural features are analyzed for the active sites of the two most important hydrogenases. Reactivity is emphasized, focusing on mechanism and catalysis. Through this analysis, gaps are identified in the synthesis of functional replicas of these fascinating and potentially useful enzymes.

Address: UMR CNRS 6521, Université de Bretagne Occidentale, CS 93837, 29238 Brest cedex 3, France. [email protected]

DOI: 10.1039/b801796b

Link outs

Free resources

Full Text Sources:

Other Literature Sources:

https://www.lens.org/lens/search/patent/list?q=ref...

Subscription / membership required

Full Text Sources:

https://doi.org/10.1039/b801796b

MeSH Terms: Bacterial Proteins, Biocatalysis, Biomimetics, Catalytic Domain, Clostridium, Desulfovibrio desulfuricans, Ferric Compounds, Hydrogen, Hydrogenase, Iron, Oxidation-Reduction, Small Molecule Libraries, Sulfhydryl Compounds