Dapsone-induced photosensitivity: a rare clinical presentation.

Bikash Ranjan Kar

Journal: Photodermatology, photoimmunology & photomedicine 2008;24(5):270-1

PMID: 18811870

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Abstract

Dapsone is an efficient anti-inflammatory and antimycobacterial agent. It is one of the main constituents of multidrug therapy (MDT). It acts by interference with folate metabolism. Dapsone-induced photosensitivity is a rare, non-dose-related adverse effect of the sulfone and can occur in patients with inflammatory skin disorders treated with dapsone. So far, only 12 cases seem to have been reported in the literature. We report a case of dapsone-induced photosensitivity in an Indian patient with leprosy.

Address: Department of Dermatology, Institute of Medical Sciences & SUM Hospital, Orissa, India. [email protected]

DOI: 10.1111/j.1600-0781.2008.00372.x

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MeSH Terms: Adult, Dapsone, Humans, India, Leprostatic Agents, Leprosy, Lepromatous, Male, Photosensitivity Disorders