Safety of a novel treatment to improve sperm motility in men with spinal cord injury.

Emad Ibrahim, Nancy L Brackett, Teodoro C Aballa, Charles M Lynne

Journal: Fertility and sterility 2009;91(4 Suppl):1411-3

PMID: 18692817

Free Full Text on Elsevier Science View on PubMed

Abstract

Seminal plasma of men with spinal cord injury (SCI) contains high concentrations of cytokines. Neutralizing these target cytokines did not damage sperm DNA or sperm viability, indicating that this method may hold promise as a safe therapy for improving sperm motility in men with SCI.

Address: Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, Miami, Florida 33136, USA. [email protected]

DOI: 10.1016/j.fertnstert.2008.05.027

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MeSH Terms: Antibodies, Monoclonal, Cell Survival, Cytokines, DNA Fragmentation, Humans, Infertility, Male, Male, Receptors, Cytokine, Reproductive Techniques, Assisted, Sodium Chloride, Sperm Motility, Spermatozoa, Spinal Cord Injuries