A diffusive model of the ball and chain inactivation.

Przemyslaw Borys, Zbigniew J Grzywna

Journal: Bio Systems 2009;94(3):267-9

PMID: 18721853

Full Text on Elsevier Science View on PubMed

Abstract

The ball and chain mechanism is a widely accepted theory for the inactivation of the Shaker K(+)channel. In this paper we propose a diffusive model that predicts a rate of inactivation that is comparable to the experimental measurements.

Address: Department of Physical Chemistry and Technology of Polymers, Section of Physics and Applied Mathematics, Silesian University of Technology, Ks M Strzody 9, Gliwice, Poland. [email protected]

DOI: 10.1016/j.biosystems.2008.06.012

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MeSH Terms: Cell Membrane, Models, Chemical, Peptides, Protein Conformation, Shaker Superfamily of Potassium Channels