Atypical ischemic lower extremity ulcerations: a differential diagnosis.

Steven M Dean

Journal: Vascular medicine (London, England) 2008;13(1):47-54

PMID: 18372440

Abstract

Severe peripheral artery disease (PAD) is the predominant cause of ischemic ulcerations involving the lower extremities. PAD-associated ulcerations are typically distally located involving the feet, toes, and sometimes the calves. In contradistinction, atypical ischemic ulcerations of the lower extremity are often non-atherosclerotic in etiology, involve the proximal leg (thigh/buttocks), can evolve despite palpable distal pulses, and may coexist with other cutaneous aberrations (e.g. macules, purpura, nodules, and livedo reticularis). A differential diagnosis of atypical ischemic ulcerations involving the legs is presented.

Address: Department of Cardiovascular Medicine, The Ohio State University, Columbus, Ohio 43210, USA. [email protected]

DOI: 10.1177/1358863X07084729

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MeSH Terms: Anticoagulants, Antiphospholipid Syndrome, Calciphylaxis, Diagnosis, Differential, Drug Eruptions, Embolism, Cholesterol, Heparin, Humans, Ischemia, Leg Ulcer, Lower Extremity, Peripheral Vascular Diseases, Spider Bites, Vasculitis, Warfarin