Microbial rhodopsins: scaffolds for ion pumps, channels, and sensors.

Johann P Klare, Igor Chizhov, Martin Engelhard

Journal: Results and problems in cell differentiation 2008;45():73-122

PMID: 17898961

Abstract

Microbial rhodopsins have been intensively researched for the last three decades. Since the discovery of bacteriorhodopsin, the scope of microbial rhodopsins has been considerably extended, not only in view of the large number of family members, but also their functional properties as pumps, sensors, and channels. In this review, we give a short overview of old and newly discovered microbial rhodopsins, the mechanism of signal transfer and ion transfer, and we discuss structural and mechanistic aspects of phototaxis.

Address: Fachbereich Physik, University Osnabrück, Barbarastrasse 7, 49069, Osnabrück, Germany.

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