Human cathepsin D.

Alina Minarowska, Marek Gacko, Alicja Karwowska, Łukasz Minarowski

Journal: Folia histochemica et cytobiologica 2008;46(1):23-38

PMID: 18296260

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Abstract

A literature survey was performed of human cathepsin D gene, cathepsin D biosynthesis, posttranslatory modifications, transport within the cell, substrate specificity and catalytic effect. Methods used to determine the activity and level of this proteinase as well as its role in the biochemistry and pathobiochemistry of cells, tissues and organs were considered.

Address: 3rd Department of Children's Diseases, Medical University, Bialystok, Poland. [email protected]

DOI: 10.2478/v10042-008-0003-x

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MeSH Terms: Amino Acid Sequence, Cathepsin D, Humans, Molecular Sequence Data, Protein Processing, Post-Translational, Substrate Specificity