Cytotoxicity, histopathological, microbiological and clinical aspects of an endodontic iodoform-based paste used in pediatric dentistry: a review.

Daniella Ferraz Cerqueira, Anna Carolina Volpi Mello-Moura, Elaine Marcílio Santos, Antonio Carlos Guedes-Pinto

Journal: The Journal of clinical pediatric dentistry 2008;32(2):105-10

PMID: 18389674

Free Full Text on MRE Press View on PubMed

Abstract

This review aims at describing and comparing materials commonly used in root canal therapy, the cytotoxicity, histopathological, microbiological and clinical aspects ofa iodoform-based paste (Guedes-Pinto Paste-GPP) used in endodontic treatment of primary teeth. GPP has shown excellent biocompatibility to pulp fibroblasts and mild inflammatory reactions, having been well-tolerated by the periapical and connective tissues. Moreover, GPP bactericidal and bacteriostatic effects against many oral microorganisms were also demonstrated. Regarding clinical trials, the GPP technique has achieved success rates when considering clinical and radiographic examinations. In the face of all the above mentioned results, this paper would like to propose the use of this endodontic material as a root canal filling for primary teeth.

Address: Departamento de Ortodontia e Odontopediatria, Faculdade de Odontologia, Universidade de Sao Paulo, Brazil. [email protected]

DOI: 10.17796/jcpd.32.2.k1wx5571h2w85430

Link outs

Free resources

Full Text Sources:

https://www.jocpd.com/articles/10.17796/jcpd.32.2....

Medical:

Subscription / membership required

Full Text Sources:

https://meridian.allenpress.com/jcpd/article-looku...

MeSH Terms: Camphor, Child, Child, Preschool, Chlorophenols, Dental Care for Children, Dental Caries, Dental Pulp Cavity, Dental Restoration, Permanent, Drug Combinations, Humans, Hydrocarbons, Iodinated, Pediatric Dentistry, Polyethylene Glycols, Prednisolone, Rifamycins, Root Canal Filling Materials, Tooth, Deciduous