Pericytes and ocular diseases.

Andrius Kazlauskas, Rūta Motiejūnaite

Journal: Experimental eye research 2008;86(2):171-7

PMID: 18078933

Full Text on Elsevier Science View on PubMed

Abstract

Pericytes are vascular mural cells which play multiple roles in angiogenesis and maintenance of blood vessel morphology and stability. In this review, we analyze recent data on the participation of pericytes in the pathogenesis of proliferative and non-proliferative diabetic retinopathy, as well as an emerging role in other angiogenic ocular diseases such as retinopathy of prematurity. Ways to exploit pericytes as targets for treatment of ocular diseases are discussed.

Address: Schepens Eye Research Institute, Harvard Medical School, Boston, MA 02114, USA.

DOI: 10.1016/j.exer.2007.10.013

Link outs

Free resources

Medical:

https://medlineplus.gov/eyediseases.html

Other Literature Sources:

https://www.lens.org/lens/search/patent/list?q=ref...

Subscription / membership required

Full Text Sources:

MeSH Terms: Angiogenesis Inhibitors, Choroidal Neovascularization, Corneal Neovascularization, Diabetic Retinopathy, Eye Diseases, Humans, Infant, Newborn, Infant, Premature, Neovascularization, Pathologic, Pericytes, Retinal Vessels, Retinopathy of Prematurity