Primary hyperparathyroidism and familial hyperparathyroid syndromes.

Miriam Blackburn, Terry Diamond

Journal: Australian family physician 2008;36(12):1029-33

PMID: 18075629

Free Full Text on Australian Family Physician View on PubMed

Abstract

BACKGROUND

Ninety percent of cases of hypercalcaemia are due to primary hyperparathyroidism or hypercalcaemia of malignancy.

OBJECTIVE

This article outlines the diagnostic features of primary hyperparathyroidism and determines who would benefit from parathyroidectomy. It also aims to raise awareness of familial hyperparathyroid syndromes.

DISCUSSION

Diagnosis of primary hyperparathyroidism requires hypercalcaemia, elevated or inappropriately normal serum parathyroid hormone and a fractional urinary excretion of calcium greater than 0.02. Many patients benefit from parathyroidectomy, which has a high rate of cure.

Address: Department of Endocrinology, University of New South Wales, St. George Hospital Campus. [email protected]

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https://www.racgp.org.au/afp/200712/21053

MeSH Terms: Adult, Aged, Female, Humans, Hypercalcemia, Hyperparathyroidism, Hyperparathyroidism, Primary, Male, Middle Aged, Multiple Endocrine Neoplasia Type 1, Multiple Endocrine Neoplasia Type 2a, Parathyroid Hormone