Internalins: a complex family of leucine-rich repeat-containing proteins in Listeria monocytogenes.

H Bierne, C Sabet, N Personnic, P Cossart

Journal: Microbes and infection 2008;9(10):1156-66

PMID: 17764999

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Abstract

The Listeria monocytogenes genome includes a large family of proteins harbouring leucine-rich repeats known as internalins (Inl). The generation of novel mutants and comparative analysis of Inl variability among Listeria and other bacterial genomes suggest that beyond the extensively-studied invasins, InlA and InlB, additional internalins also play important functions in the infectious process.

Address: Unité des Interactions Bactéries-Cellules, INSERM U604, INRA USC2020, Institut Pasteur, F-75015 Paris, France. [email protected]

DOI: 10.1016/j.micinf.2007.05.003

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MeSH Terms: Amino Acid Sequence, Bacterial Proteins, Imaging, Three-Dimensional, Leucine-Rich Repeat Proteins, Listeria monocytogenes, Models, Molecular, Molecular Sequence Data, Proteins